Search results for " covalent grafting"

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Biocompatible Poly(N-isopropylacrylamide)-halloysite Nanotubes for Thermoresponsive Curcumin Release

2015

The grafting of poly(N-isopropylacrylamide) (PNIPAAM) onto the halloysite external surface is proposed in order to obtain a novel thermoresponsive drug carrier for curcumin delivery. The new nanomaterial is characterized by means of FT-IR spectroscopy, thermogravimetric analysis, and SEM investigations. A high density of polymer chain was achieved at the nanoparticle surface. The PNIPAAM dehydration phenomenon was observed in water above 32 °C that is nearly coincident with the lower critical solution temperature for the polymer. The colloidal stability as well as the wettability of the obtained nanomaterial may be triggered by temperature stimuli. In vitro tests simulating the gastro-intes…

chemistry.chemical_classificationThermogravimetric analysisMaterials scienceNanoparticleNanotechnologySettore CHIM/06 - Chimica OrganicaPolymerengineering.materialLower critical solution temperatureHalloysiteSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsNanomaterialschemistry.chemical_compoundGeneral EnergychemistryPoly(N-isopropylacrylamide)engineeringPhysical and Theoretical ChemistryDrug carrierhalloysite nanotubes PNIPAAM covalent grafting curcumin releaseSettore CHIM/02 - Chimica FisicaThe Journal of Physical Chemistry C

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